Orogenital ulcers, SLE and hydralazine.

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Orogenital ulcers, SLE and hydralazine.

The case is reported of a man developing drug-induced systemic lupus erythematosus while taking hydralazine. The illness was characterized by arthritis and a purpuric rash particularly in the light-sensitive areas as well as orogenital and cutaneous ulceration. Anti-nuclear antibody and DNA binding were positive. All clinical manifestations disappeared on withdrawal of hydralazine.

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A 25-Year-Old Male with Orogenital Ulcers, Rash, and Difficulty Swallowing

A 25-year-old otherwise healthy male presented with new-onset odynophagia, rash, and orogenital ulcers. Despite treatment with antibiotics for presumed bacterial pharyngitis, the patient remained symptomatic, with abnormal vital signs and laboratory values. Upon dermatology consultation and histopathologic correlation, he was diagnosed with Behçet disease. Behçet disease is a rare rheumatologic...

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Hydralazine and Male Impotence

CHEST, 78: 2, AUGUST, 1980 edema, pseudocyst formation or development of fibrous penpancreatic adhesions may all lead to obstruction of the intestinal lymphatics as they converge into the root of the mesentery in the region of the uncinate process of the pancreas and cause chylous ascites.’ The association of chylous ascites and chylothorax has been documented.’ Intraperitoneal injection of con...

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Ocular and neurological Behçet's disease without orogenital ulceration?

A 28 year old West Indian patient is described who had a relapsing and remitting steroid-sensitive illness for 3 years. The clinical features included uveitis and widespread CNS involvement. The patient was treated as though he had neurosarcoidosis. Post mortem examination revealed histological changes compatible with a diagnosis of Behçet's disease, but at no time did he suffer from oral or ge...

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Effect of Hydralazine

The effects of hydralazine on aortic rupture, hemodynamics and aortic ultrastructure were studied in turkeys fed B-aminopropionitrile (BAPN). A mortality rate of 24% due to hemopericardium and internal hemorrhage in turkeys fed only BAPN increased to 91% when turkeys were fed both BAPN and hydralazine, despite a significant reduction in blood pressure after both drugs. Death rates among turkeys...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1981

ISSN: 0032-5473

DOI: 10.1136/pgmj.57.668.378